Comparisons between tree topologies provide important information for many evolutionary studies. TreeKo is a method that allows the comparison of any two tree topologies. Even those with missing leaves and duplications. This is important in genome-wide analysis. Since many trees do not have exact leaf pairings and therefore most tree comparison methods are rendered useless. In order to calculate the distance between two trees that contain duplications, treeKo first prunes the trees.

Trn4 has a full-screen, color, mouse-aware interface, including an option selector to control the most common configuration settings. And its derivatives - Ubuntu, Lubuntu, Mint, et al.

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